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Faculty

Department of Biochemistry and Cell Biology

Paul M. Bingham Genetic control of development and gene expression in animals
Deborah Brown Cholesterol/sphingolipid-rich domains in membrane signaling
Kevin Czaplinski Post-transcriptional control of gene expression in the nervous system
Vitaly Citovsky Nuclear targeting and intercellular communication in plants
Neta Dean Glycosylation; fungal pathogenesis
Dale G. Deutsch Marijuana; molecular neurobiology of anandamide
J. Peter Gergen Gene expression and development in Drosophila
Robert Haltiwanger Glycobiology; biosynthesis, structure, and function
Bernadette C. Holdener Genetic regulation of early mammalian development
Nancy Hollingsworth Meiotic synapsis, recombination, and segregation in yeast
Wali Karzai Structure and function of RNA-binding proteins and biochemical studies of the SmpB•tmRNA quality control system
William J. Lennarz Biosynthesis and function of glycoproteins in cell-cell interactions
Erwin London Membrane protein structure/translocation/folding
Harvard Lyman Photocontrol of chloroplast development
Kenneth B. Marcu Antibody class switch mechanism; NFkB kinases; Myc gene control
Aaron Neiman Vesicle trafficking and membrane/cytoskeletal interactions
Nisson Schechter Homeobox and filament proteins in neuronal differentiation
Sanford Simon Extracellular degradation by neutrophil proteases
Steven Smith Structure and function of membrane proteins
Rolf Sternglanz Chromatin structure and function; gene expression; HATs
Gerald H. Thomsen Growth factors /signal transduction in early vertebrate development
 

Department of Chemistry

Elizabeth Boon Nitric oxide signaling in bacteria.
Isaac Carrico Site-specific protein labeling; glycoproteins.
Carlos Simmerling Development of tools for efficient and simulation of chemical systems and using them to study the structure and dynamics of molecules involved in biological processes.
Peter Tonge Spectroscopic insights into enzyme mechanisms and structure
   

Department of Medicine

Jian Cao, M.D. Biology and prevention of cancer metastasis
Wen-Tien Chen Proteases / integrins in cancer invasion, metastasis, angiogenesis
J. Craig Cohen Organogenesis
Berhane Ghebrehiwet Biochemistry; function of the complement system
Yaacov Hod Hormonal control of gene expression; mRNA turnover
Jolyon Jesty Regulatory controls of blood coagulation
Erich R. Mackow Rotavirus and Hantavirus Pathogenesis
Richard Lin Kinase signaling and cell proliferation
Mario Rebecchi Phospholipases and signal transduction
Roy Steigbigel Immune dysfunction induced by HIV infection
William Van Nostrand Vascular functions of Alzheimer's disease amyloid beta-protein
 

Department of Molecular Genetics & Microbiology

Jorge Benach
Pathogenesis of spirochetal infections and their host responses
Nicolas Carpino Positive and Negative Regulation of T cell Receptor Signaling
Bruce Futcher Cell cycle, cyclins, and yeast genetics
Michael Hayman Viral/cellular oncogenes; differentiation of erythroid cells
Patrick Hearing Adenovirus regulation of cellular proliferation and gene expression; adenovirus vectors for human gene therapy
James Konopka Hormone signal transduction; yeast cell development
Janet Leatherwood Cell cycle control and DNA replication in fission yeast
Nancy Reich Signaling switches in gene expression by hormones or viral infection.
David Thanassi Secretion of virulence factors by bacterial pathogens; pilus biogenesis by uropathogenic Escherichia coli
Eckard Wimmer RNA virus genetics, replication, pathogenicity, cellular receptors
Wei-Xing Zong Molecular regulation of apoptotic and necrotic cell death.
 

Department of Neurobiology and Behavior

Simon Halegoua Molecular control of the neuronal phenotype
Maurice Kernan Molecular basis of mechanical senses
Joel Levine Cell-surface molecules of the developing nervous system
David McKinnon Molecular physiology of sympathetic neurons and cardiac muscle
Howard Sirotkin Genetic and molecular analysis of early vertebrate development
 

Department of Oral Biology and Pathology

Soosan Ghazizadeh Epithelial stem cell biology; Skin bioengineering and gene therapy.
 

Department of Pathology

Fleit, Howard B. Leukocyte Fc receptors; macrophage differentiation
Martha Furie Interactions between leukocytes and endothelium
Richard R. Kew Leukocyte chemotaxis/inflammation
Ute Moll Tumor suppressor genes; mechanism of p53 inactivation
Kenneth Shroyer Cancer biomarkers as diagnostic adjuncts in cervical pathology and cytopathology; cervical cancer and HPV
Eric Spitzer Molecular biology of Cryptococcus neoformans
Gary Zieve Assembly/transport of snRNP particles
 

Department of Pharmacological Sciences

Miguel Berrios Cell structure and function; the cell biology of DNA damage and repair.
Bogenhagen, Daniel Mitochondrial DNA; DNA repair
Emily Chen Breast Cancer Metastasis & Shotgun Proteomics
Holly Colognato Extracellular matrix in the brain; roles during development and during neurodegeneration.
Miguel Garcia Diaz Consortium for Inter-Disciplinary Environmental Research
Michael A. Frohman Early mammalian development; gene regulation
Arthur Grollman Mechanisms of chemical mutagenesis/carcinogenesis
Craig C. Malbon Heterotrimetric G-proteins in development and cancer
Masaaki Moriya Cellular responses to DNA damage.
Joav Prives Cytoskeletal membrane interactions in muscle cells
Orlando Schärer Chemical Biology of DNA damage and repair.
Ken-Ichi Takemaru Wnt Signaling in Development and Disease
Styliani-Anna Tsirka Neuronal-microglial interactions in the central nervous system
 

Department of Physiology and Biophysics

Mark Bowen Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds
Roger A. Johnson Intercellular and intracellular signal transduction
Stuart McLaughlin Calcium/phospholipid second messenger system
W. Todd Miller Tyrosine phosphorylation and signal transduction
Suzanne Scarlata Structure/oligomerization of membrane proteins
Ilan Spector Neuronal differentiation and microfilaments
Hsien-yu Wang Signal transduction and development.
Thomas White Molecular biology and physiology of gap junction channels
 

Brookhaven National Laboratory

John Dunn Structure/function of bacteriophage T7 RNA polymerase
Richard Setlow DNA damage and repair; carcinogenesis in fish
F. William Studier Phage T7 replication; large-scale nucleotide sequencing
 

Cold Spring Harbor Laboratory

Gregory Hannon Growth control in mammalian cells; post-transcriptional gene silencing
Leemor Joshua-Tor Structural biology; nucleic acid regulation; RNAi; molecular recognition; X-ray crystallography
Adrian Krainer mRNA splicing; gene expression; RNA-protein interaction
Yuri Lazebnik Molecular mechanism of apoptosis
Scott Lowe Modulation of apoptosis; chemosensitivity; senescence by cancer genes
Robert Martienssen Plant genetics; transposons; development; gene regulation; DNA methylation
Alea Mills Cancer; development; aging; senescence; epigenetics
Senthil K. Muthuswamy Understanding cancer initiation using three-dimensional epithelial structures
David L. Spector Spatial organization of gene expression
Arne Stenlund DNA replication of papillomaviruses
Bruce Stillman DNA replication and chromatin assembly in human and yeast cells
William P. Tansey Regulation of oncoprotein stability
Nicholas K. Tonks Characterization of protein tyrosine phosphatases
Linda Van Aelst Signal transduction; Ras and Rac proteins, tumorigenesis
Michael H. Wigler Growth control in yeast and mammalian cells
   
Department of Applied Mathematics and Statistics
John Reinitz Systems biology of Drosophila development and transcription
   
   

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